general hospital, krol kol yiding with a big rig. witnesses tell police the driver, traveling east on oak street may have run a red light. and a 52-year-old psychiatrist and associate professor was thrown from a bus and killed. three other passengers and the shuttle driver suffered minor injuries. >> drivers are used to terrible gridlock in los angeles but are they ready for carmeggodon that. is what they're calling a closure of the 405. officials say they're ready and got out to make sure everybody is aware state wide. there are warning signs on 580 here in the bay area for drivers who may be heading down south. and we are live from l.a. now z everybody is expecting that this is going to be a huge mess down there. and you know we've been hearing about this for weeks and forget king kong. the threat is carmeggodon. when you shut down a freeway it does feel like the end of the world. >> if you live in l.a. you know what is coming. the famed 405, yes that 405 is filled with 500,000 cars on a weekend this, weekend it's anything but typical. for 53 hours a 10-mile stretch will be closed. why?